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Reductive metabolism of nitrofurantoin in the rat.

Hepatic estrone and estradiol glucuronyltransferase activity in pregnancy. Induction by pretreatment with 3-methylcholanthrene and phenobarbital.

Role of cytochrome b5 in NADPH-and NADH-dependent hydroxylation by the reconstituted cytochrome P-450- or P-448-containing system.

Mutagenic evaluation of nitrofuran derivatives in Salmonella typhimurium, by the micronucleus test, and by in vivo cytogenetics.

Organic solvent extraction of liver microsomal lipid. Effect on the kinetic parameters of benzo[a]pyrene hydroxylase and benzphetamine N-demethylase activity.

The effect of pregnancy on the metabolism of [14C]phenytoin in the isolated perfused rat liver.

The effect of pregnancy on the biliary excretion of [14C]phenytoin in the rat.

Identification of an anion-transport ATPase that catalyzes glutathione conjugate-dependent ATP hydrolysis in canalicular plasma membranes from normal rats and rats with conjugated hyperbilirubinemia (GY mutant).

Prolactin regulates maternal bile secretory function post partum.

Mirex exposure inhibits the uptake of estradiol-17 beta(beta-D-glucuronide), taurocholate, and L-alanine into isolated rat hepatocytes.

Mirex inhibits bile acid secretory function in vivo and in the isolated perfused rat liver.

Hepatic clearance and biliary secretory rate maximum of taurocholate in the recirculating and single pass isolated perfused rat liver. Effects of the cholestatic agent, estradiol-17 beta-(beta-D-glucuronide).

Characterization of [3H]estradiol-17 beta-(beta-D-glucuronide) binding sites in basolateral and canalicular liver plasma membranes.

Predictors of response to high dose antipsychotics in chronic schizophrenics.

Methylphenidate plasma concentrations in chronically and acutely treated latency-age children.

Structure-activity relationship of the cholestatic activity of dihydrotestosterone glucuronide, allo bile acids and lithocholate.

Monokine depression of bile flow in the isolated perfused rat liver.

Effects of taurocholate infusion on biliary excretion in isolated perfused rat livers. Decreased biliary excretion of dibromosulfophthalein in pregnancy.

Estrogen cholestasis. Membranes, metabolites, or receptors?

Coregulation of C3-hydroxyl versus C17-hydroxyl glucuronidation of beta-estradiol in pregnancy and after treatment with phenobarbital or ethinyl-estradiol.

Characterization of covalent binding of N'-nitrosonornicotine in rat liver microsomes.

High and low affinity binding of [3H]cholate to rat liver plasma membranes.

Binding of 3H-estradiol-17 beta-(beta-D-glucuronide), a cholestatic organic anion, to rat liver plasma membranes. Evidence consonant with identification of organic anion carriers.

Multiple carriers for uptake of [3H]estradiol-17 beta(beta-D-glucuronide) in isolated rat hepatocytes.

Taurocholate and steroid glucuronides: mutual protection against cholestasis in the isolated perfused rat liver.

Effects of phenobarbital and SKF-525A on in vitro hepatic metabolism of verapamil and nifedipine.

Cardiovascular and pharmacokinetic consequences of combined administration of verapamil and propranolol in dogs.

Effect of hypoxia and pregnancy on antipyrine metabolism in isolated perfused rat livers.

Organic solvent extraction of liver microsomal lipid. I. The requirement of lipid for 3,4-benzpyrene hydroxylase.

Liver microsomal electron transport systems. II. The involvement of cytochrome b5 in the NADH-dependent hydroxylation of 3,4-benzpyrene by a reconstituted cytochrome P-448-containing system.

Role of cytochrome b5 in hydroxylation by a reconstituted cytochrome P-450-containing system.

The metabolism of 1-n-butyl-5,5-diethylbarbituric acid (N-n-butyl barbital) in the rat.

Hepatic morphine and estrone glucuronyltransferase activity and morphine biliary excretion in the isolated perfused rat liver. Effect of pregnancy and estradiol-17 beta treatment.

The effect of pregnancy and estradiol-17 beta treatment on the biliary transport maximum of dibromosulfophthalein, and the glucuronide conjugates of 5-phenyl-5-p-hydroxyphenyl[14C]hydantoin and [14C]morphine in the isolated perfused rat liver.

The effect of pregnancy and treatment with 17 beta-estradiol on the transport of organic anions into isolated rat hepatocytes.

Hepatotoxic effects of estradiol-17 beta-D-glucuronide in the rat and monkey.

Steroid D-ring glucuronides: characterization of a new class of cholestatic agents.

Characterization of uptake of steroid glucuronides into isolated male and female rat hepatocytes.

Characterization of the interaction between estrogen metabolites and taurocholate for uptake into isolated hepatocytes. Lack of correlation between cholestasis and inhibition of taurocholate uptake.

Gas-chromatographic quantification of methylphenidate in plasma with use of solid-phase extraction and nitrogen-sensitive detection.

Ethynylestradiol-17 beta D-ring glucuronide conjugates are potent cholestatic agents in the rat.

Steroid D-ring glucuronides: characterization of a new class of cholestatic agents in the rat.

The effect of diethylstilbestrol treatment on the metabolism and biliary excretion of [14C]phenytoin in the isolated perfused rat liver.

The metabolism of 1-n-butyl-5,5-diethylbarbituric acid (N-n-butyl barbital) in the rat. II. Distribution of the drug and its metabolites in various tissues in vivo and in the isolated perfused liver system.

Characterization of cholestasis induced by estradiol-17 beta-D-glucuronide in the rat.

The effect of estradiol-17 beta treatment on the metabolism and biliary excretion of phenytoin in the isolated perfused rat liver and in vivo.

Expression of an epidermal keratin protein in liver of transgenic mice causes structural and functional abnormalities.

Prolactin increases mRNA encoding Na(+)-TC cotransport polypeptide and hepatic Na(+)-TC cotransport.

Carrier-mediated electrogenic transport of estradiol-17 beta-glucuronide in rat liver BMV.

Prolactin increases hepatic Na+/taurocholate co-transport activity and messenger RNA post partum.



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