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Defective activation by glucose of hepatic glycogen synthesis in the obese hyperglycaemic mouse.
People related with this object:

S A Smith
M A Cawthorne
A L Levy
D L Simson
 
Object description
The administration of an oral glucose load to 24 h-starved lean (+/?) male C57BL/6 mice produced a rapid, 7-fold increase in the rate of hepatic glycogen synthesis and a sustained activation of glycogen synthase. In contrast, glucose produced only a small (4.5-fold), short-lived increase in hepatic glycogen synthesis in genetically obese (ob/ob) mice and no activation of glycogen synthase.02646021Biochem J. 1983 Nov 15;216 (2):491-4
Created
1983-11-15 00:00:00
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